منابع مشابه
Modeling Kick-Kill Strategies toward HIV Cure
Although combinatorial antiretroviral therapy (cART) potently suppresses the virus, a sterile or functional cure still remains one of the greatest therapeutic challenges worldwide. Reservoirs are infected cells that can maintain HIV persistence for several years in patients with optimal cART, which is a leading obstacle to eradicate the virus. Despite the significant progress that has been made...
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this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...
Landscape review of current HIV ‘kick and kill’ cure research - some kicking, not enough killing
BACKGROUND Current antiretroviral therapy (ART) used to treat human immunodeficiency virus (HIV) patients is life-long because it only suppresses de novo infections. Recent efforts to eliminate HIV have tested the ability of a number of agents to reactivate ('Kick') the well-known latent reservoir. This approach is rooted in the assumption that once these cells are reactivated the host's immune...
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wo new studies indicate that cycles of phosphorylation and dephosphorylation may be required during clathrin-mediated endocytosis. A newly identified kinase is responsible for the required phosphorylation. Clathrin and the adaptor protein 2 (AP2) complex are the major coat proteins of clathrin-coated vesicles (CCVs). Among components of the AP2 complex are ␣ and  2 adaptins, which mediate AP2 ...
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در هر برنامه آموزشی، مهم ترین فاکتور موثر بر موفقیت دانش آموزان کتاب درسی است (مک دونو و شاو 2003). در حقیقت ، کتاب قلب آموزش زبان انگلیسی است( شلدن 1988). به دلیل اهمیت والای کتاب به عنوان عنصر ضروری کلاس های آموزش زبان ، کتب باید به دقت ارزیابی و انتخاب شده تا از هرگونه تاثیر منفی بر دانش آموزان جلوگیری شود( لیتز). این تحقیق با طراحی پرسش نامه ارزیابی کتاب که فرصت ارزیابی معتبر را به اساتید د...
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ژورنال
عنوان ژورنال: AIDS
سال: 2019
ISSN: 0269-9370
DOI: 10.1097/qad.0000000000002148